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Diabetes drug Mounjaro approved by UK regulator to help obese and overweight people lose weight | Science & Tech News

A diabetes drug has been approved by a UK regulator to help obese and overweight adults lose weight.

Patients with weight-related health problems – such as prediabetes, high blood pressure, high cholesterol or heart problems – will have access to the drug Mounjaro privately after it was approved by the Medicines and Healthcare Products Regulatory Agency (MHRA).

It needs further approval from the National Institute for Health and Care Excellence (NICE) to be made available on the NHS.

Health Secretary Steve Barclay said: “Although further approvals are needed to use this in the NHS, Mounjaro has the potential to help thousands of people living with obesity and support those suffering from weight-related illnesses – if used alongside diet and physical activity.

“Tackling obesity could help cut waiting lists and save the NHS billions of pounds.”

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The active ingredient in the drug – tirzepatide – works by making a patient feel full and less hungry, and making them experience fewer food cravings.

The MHRA’s authorisation is based on the results of two clinical trials, one of which showed patients who received the highest dose of the drug lost 22.5% of their body weight over a 72-week period.

The second showed patients with Type-2 diabetes lost 15.7% of their body weight over 72 weeks.

The trials showed patients treated with Mounjaro “had a significant weight loss over time compared to patients who took a placebo”.

The agency listed the potential side effects of the medicine, including nausea, diarrhoea, vomiting – which usually goes away over time – and constipation.

Low blood sugar is also “very common” in patients with diabetes, it added.

It also warned the drug may affect how well the contraceptive pill works in obese or overweight female patients.

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This notice was published: 2023-11-08 22:11:00

By Sky News

Sky News is a British 24-hour information television channel, the first in Europe of its kind, launched on February 5, 1989 by the British Sky Broadcasting Company.

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